| 22/11 | CSKA Moscow | 0-2 | Lille |
| 22/11 | Bayern | 3-1 | Villarreal |
| 22/11 | Napoli | 2-1 | Man City |
| 22/11 | Trabzonspor | 1-1 | Inter |
| 22/11 | Otelul Galat | 2-3 | FC Basel |
| 22/11 | Man Utd | 2-2 | Benfica |
| 22/11 | Lyon | 0-0 | Ajax |
| 22/11 | Real Madrid | 6-2 | D Zagreb |
| 23/11 | Zenit | 0-0 | Al Nicosia |
| 23/11 | BATE Borisov | 0-1 | V Plzen |
| 23/11 | Leverkusen | 2-1 | Chelsea |
| 23/11 | Valencia | 7-0 | Genk |
| 23/11 | Marseille | 0-1 | Olympiakos |
| 23/11 | Arsenal | 2-1 | Dortmund |
| 23/11 | Shakhtar D | 0-2 | FC Porto |
| 23/11 | Milan | 2-3 | Barcelona |
